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Description

Six patients suffered from thalassemia major (TM), four from sickle cell disease (SCD) and two of them from severe congenital neutropenia (SCN)

Abstract Maintaining the balance of a cells redox function is key to determining cell fate

GSH is synthesized in a two-step reaction catalyzed by -glutamylcysteine synthetase and GSS in the -glutamyl cycle, which includes an additional four enzymes (Figure 1)