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With a dose-dependent response, the serum level of cotinine, the primary metabolite of nicotine catabolism, was correlated with increased naive (CD45RA + ) and decreased memory (CD45RO + ) CD3 + CD4 + T cells

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Approximately 10-15 vape puffs are equal to a cigarette, although nicotine absorption may differ between smoking and vaping

GC-MS analysis of MCS Agilent 7890 A gas chromatograph (Agilent, Palo Alto, CA, USA) equipped with Agilent DB-5MS column (60.0 m 0.25 mm 0.25 m, Agilent, USA), and coupled to Agilent 5977 C mass spectrometer (Agilent, Palo Alto, CA, USA) was used for the chemical composition of MCS analysis