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[4] Antioxidanten keren het tij Verlaagd antioxidanten niveau bij insulineresistentie De meeste menselijke cellen gebruiken glucose als hun belangrijkste brandstof, waarbij de opname van glucose in de cellen afhankelijk is van insuline

As such, interventions aimed to reduce SOD1 G93A expression and/or SOD1 G93A protein accumulation are most likely to achieve large rescuing effects in this model, whereas interventions that do not directly target the SOD1 G93A mechanisms are less likely to achieve success in retarding motor neuron disease of this model 23,24,25

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Many compounds that showed promise in animal stroke models failed to translate to humans in clinical trials