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By identifying the specific region of growth hormone responsible for lipolytic activity (amino acids 176-191) and isolating this fragment, scientists created a targeted intervention with improved safety profile, fewer contraindications, reduced side effects, and simpler monitoring requirements compared to full growth hormone

Maar, K., Hetenyi, R., Maar, S., Faskerti, G., Hanna, D., Lippai, B., Takatsy, A., & Bock-Marquette, I

Both compounds produce large body-weight reductions in obesity trials, and both are once-weekly subcutaneous injections dominated by gastrointestinal side effects