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PAGA polymers can be prepared using methods known in the art (e.g., as described in U.S

Alzheimers disease (AD), a neurological disorder of memory loss and changes in behaviour, is associated with the accumulation of amyloid protein plaques because of the intracellular neurofibrillary tangled (NFT) aggregation produced by abnormally hyper phosphorylated tau () protein

By integrating mechanistic, preclinical, and clinical evidence, this review seeks to position capsaicin as a plausible natural multitarget therapeutic candidate and to provide a conceptual framework for future interventions targeting the complex pathophysiology of CMS

DOI: 10.1038/s41389-020-00285-9 Evans, R.M., Lippman, S.M