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Dihydropyrimidine dehydrogenase (DPD) catabolizes 5-FU into inactive metabolites ( Orotate phosphoribosyltransferase (OPRT), UMP kinase, and uridine monophosphate synthetase aid in converting 5-FU into active metabolites

Taking it alongside a meal helps buffer the stomach and ensures a smoother digestive process

Klf2 contributes to the stemness and self-renewal of human bone marrow stromal cells