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A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

elegans (10 days post adulthood) treated with SIH ( Figure 3D ) revealed decreased iron associated with the LMW peak (normalized peak area approximately 40%)

However: Screen for G6PD deficiency before high-dose IV use to avoid risk of hemolysis Monitor renal function , especially in patients with renal impairment or oxalate history Caution in patients with a history of kidney stones , as high-dose vitamin C may increase urinary oxalate Storage & Handling Store at controlled room temperature (2025C / 6877F) Protect from light