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( The rest of studies also had small sample size but some had longer follow-up period (up to 18 months)

Thus, this review demonstrates the therapeutic potential of NS that could be used as a complement or adjuvant for the management of DM and its complications

Melting curves revealed no nonspecific product or primer dimers, suggesting the accuracy of mRNA transcript identification by displaying IGF1, IGF1R, GHR, and TLR4 specific primers suitable for RTPCR (Table 1)