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72 Acute fasting and pyruvate deprivation in vivo and in vitro increase glycolytic gene and protein expression in the ovaries, decrease AMPK activity, and enhance mTOR activation, which in turn leads to elevated phosphorylation of downstream proteins like Akt and FOXO3a, promoting primordial follicle activation

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This has been replicated in other small studies and a meta-analysis published in September 2020 confirmed its safety and has potential to help with the core features of autism

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