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Interestingly, GHRH-treated GH3-derived sEV significantly inhibited BRL 3A cell proliferation compared with GH3-sEV (Fig

2020;158(8):2139-2149.e14

Immunostaining for glial fibrillary acidic protein (GFAB, a marker for astrocytes) and ionized calcium-binding adapter molecule 1 (Iba-1, a marker for microglia) indicated reduced astrocyte and microglia activation in both striatum and substantia nigra