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Trimetazidine and the contractile response of dysfunctional myocardium in ischaemic cardiomyopathy

These findings indicate an extrapulmonary restrictive lung defect caused by decreased respiratory muscle strength

The extrinsic pathway is initiated by the binding of proapoptotic ligands to death receptors on the cell surface, leading to the formation of the death-inducing signaling complex (DISC) and the activation of caspases (Qiao et al., 2024)