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Importantly, despite recent research indicating distinct findings regarding the 40 Hz effect, particularly concerning amyloid load in AD 21,22 , multiple studies in both mouse models and humans have consistently affirmed the beneficial effects of GENUS on disease pathology 18,19,23,24,25,26,27,28,29,30

TBI-induced neuroinflammation further intensifies this metabolic reprogramming, with activated microglia releasing pro-inflammatory factors like IL-6 and TNF, enhancing glycolysis while suppressing OXPHOS through TLR signaling pathways (190)

Consequently, they benefit from breast milk, a potent form of chrononutrition, with its composition varying according to the mothers circadian rhythms