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Consult a healthcare provider if youre taking medications that could conflict with supplementation

Iron metabolism heavily relies on the interactions of iron response elements (IREs) and iron regulatory proteins (IRPs), collectively known as IRE-IRPs, to maintain cellular homeostasis

8b) CYP3A4 sides contacting the G-helix side of CYP2E1

For example, it has been shown that exceeding the upper limit of selenium intake (400 g/d) can lead to selenotoxicity, but no significant symptoms of toxicity were observed when selenium was ingested in the form of SeNPs (1,600 g/d), and some selenotoxicity symptoms did not occur until even an intake of 3,200 g/d (255)