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Description

To address this question, the M1 region of these PI resistant precursors was replaced with the NL4-3 derived M1 sequence and the resulting constructs were compared side-by-side to the corresponding M1-PR constructs (Fig

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In the dextran sodium sulfate (DSS) mouse model of colitis, increased macrophage ferroptosis (an iron-dependent form of cell death characterized by excessive lipid peroxidation [10, 11]) has been described in the colon as a consequence of and contributor to a pro-inflammatory milieu [12]