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For severe cases, the first dose is usually 1,000 mcg given intramuscularly every day or every other day for a week or two

PubMed, Danailova, Yana, et al

This shortfall necessitates peptide therapy to make up for the insufficiency

Nonetheless, a meta-analysis of the Chinese population concluded that patients diagnosed with MS and relapsing MS had lower serum B12 levels than controls, whereas remitting patients did not exhibit this difference [131]