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In the study by An et al

This accumulation can damage performance of pancreatic islet -cells through lipotoxicity, exacerbate impaired insulin action, impair glucose metabolism, and ultimately lead to hyperglycemia and hyperinsulinemia, creating a vicious cycle

Similar content being viewed by others Introduction Redox cycling describes the continuous reduction and oxidation cycle of a compound, forming radical intermediates capable of transferring an electron to molecular oxygen, generating the superoxide radical anion (O 2 . ) 1

The clinical challenge is to deliver sufficient quantities of antioxidants noninvasively, after Cl(2) exposure, to decrease morbidity and mortality