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Figure 2 Figure 3 Discussion With the widespread use of ICIs, irAEs have increasingly attracted the attention of clinicians

The experimental animal feed for the iron overload mouse model (Table S1) was synthesized by Jiangsu Medicience Biological Medicine Co., Ltd (Jiangsu, China)

(70) utilized a network pharmacological approach to predict anti-renal tubulointerstitial fibrosis effects via the ERK1/2 signaling pathway, a finding later confirmed in human renal tubular epithelial cells induced by high glucose