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A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer

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Note that the endogenous OLFM4 was also knocked down by shRNA in the recipient HGC-27 and AGS cells to avoid interference of OLFM4-MVs produced by these recipient cells themselves (Supplementary Fig

In summary, PHN is the result of qi stagnation and pathogens, like toxic pathogens (the inflammatory effect of virus on the nerve), accumulation of yin (blood stagnation in microcapillary), internal fire and heat, blood stasis, and obstruction of meridians in which acupuncture can stimulate qi circulation in the collaterals [8,10], activate blood movement, and eradicate pathogens [12,16]