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To investigate the effect of melatonin on phospholipase C activity in brain cells, SH-SY5Y human neuroblastoma cells were differentiated into dopamine neuronal phenotypes and treated with melatonin

CA1-specific HDAC9 deletion impairs cognitive function in young mice To determine the role of HDAC9 specifically within the hippocampal CA1 region, we employed the Cre/loxP system to induce region-specific deletion of HDAC9 in adult mice (46 months old)