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These other treatments help reduce dark spots and make skin smoother

doi: 10.1016/j.cell.2011.08.040 103 ScottRSnchez-AguileraAvan ElstKLimLDehorterNBaeSEet al

by increasing the expression of IL-12 and decreasing the gene expression of another inflammatory marker as IL-13 and TGF-1 leading to a decrease in a number of eosinophils [86]

Inversely, (PHA + MSG), (SE + MSG), (AST + MSG), (SE + AST + MSG) and (COMB + MSG) groups substantially diminished TNF- (by 32.6%, 55.7%, 58.3%, 69.5% and 83.1%, respectively) (Fig