MaP555 NHS (cell-permeable fluorogenic dye) sir Compound AN2 reduces mHTT levels
MaP555 NHS (cell-permeable fluorogenic dye) sir Compound AN2 reduces mHTT levelsMaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The good spectroscopic properties, high cell
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