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These mitochondrial-derived peptides (MDPs) have profound and distinct biological activities and provide a paradigm-shifting concept of active mitochondrial-encoded signals that act at the cellular and organismal level ( i.e

As is well known, Se deficiency can reduce selenoprotein biosynthesis, thus disrupting antioxidant defenses in male reproductive organs, and increasing the production of ROS (148)

Use of microdoses for induction of buprenorphine treatment with overlapping full opioid agonist use: the Bernese method

Redox-dependent cell signaling, growth, and survival ROS may play an essential role in receptor activation and downstream signaling (64, 122, 141, 145)