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ELISA showed that increasing the LC concentration from 80 to 160 mol/l did not result in a significant increase in the concentration of LC internalized by the cells, whilst cell viability was decreased slightly (Fig

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Despite the prolonged in vitro maturation process, mature sensory neurons within the DRG organoids exhibited extensive functional features, including excitability, synaptogenic competence, and the ability to form complex structures like muscle spindles