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Superoxide dismutase Superoxide dismutase ( SOD , EC 1.15.1.1) is any of a family of enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O 2 ) anion radical into normal molecular oxygen (O 2 ) and hydrogen peroxide (H 2 O 2 )

At the endpoint of the experiment, no significant differences in tumor volume or weight were observed between the HGC-27R-EVs-shNC and HGC-27R-EVs-shNC/PTX groups, indicating that EV-mediated chemoresistance reduced the sensitivity of GC cells to PTX treatment in vivo

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11 In addition, the NF-B pathway was constitutively activated in the ESCC cell lines