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A linear correlation (R 2 = 0.683) was found between the two methods, with agreement being stronger for highly reactive compounds

Previous studies have shown that Aedes mosquitoes have developed resistance to the three classes of commonly used insecticides (carbamates, organophosphates, and pyrethroids) in addition to the abandoned organochlorides worldwide ( Resistance mechanisms in Aedes are multifaceted, involving target site insensitivity, metabolic detoxification, and cuticular modifications, each contributing differently depending on environmental pressures and genetic factors

Consistent with this observation, we found that, 4 hours after NHK induction, steady-state expression of NHK did not differ in cells treated or not with etomoxir (Figure 3D)

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