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Kuroki M, Ariumi Y, Ikeda M, Dansako H, Wakita T, Kato N (2009) Arsenic trioxide inhibits hepatitis C virus RNA replication through modulation of the glutathione redox system and oxidative stress

In Situ Live Monitoring of Extracellular Acidosis near Cancer Cells Using Digital Microfluidics with an Integrated Optical pH Sensor Film

GSH is a cofactor and a synthetic substrate for GPX4, and it is required for the lipid repair function of GPX4 (Stockwell et al., 2017) and cystine/glutamate reverse transport system Xc- [or xCT/12 channel transmembrane protein transport protein carrier family 7 member 11 (SLC7A11) mediates the uptake of cystine to exchange the output of glutamate] was identified as the pivotal regulator for GSH synthesis (Hao et al., 2018)

Second, clinical translation should involve establishing multicenter biobanks for preterm infants to validate associations between ferroptosis biomarkers (such as cerebrospinal fluid ACSL4 levels and MRI-detected white-matter iron deposition) and motor development scores (GMFM and Bayley scales)