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5 Conclusion and future perspectives With the increase in the use of digital devices and the population aging, DED has become a common concern in contemporary society

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235 miR-29a was shown to hamper epithelial integrity and diminish the translation of claudin-1 through binding with the 3, untranslated region (UTR) at the CLDN1 transcript in an intestinal porcine epithelial cell line (IPEC-1)