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Rationale for targeting 7nAChR in ASD Postmortem examination of individuals with ASD has revealed abnormalities in cholinergic nuclei, cholinergic projections, cholinergic receptors, and growth factors responsible for the development and upkeep of cholinergic neurons [22]

found that ubiquitin-specific protease 3 (USP3) upregulated the expression of the ACOT7 protein through a deubiquitination mechanism, whereas downregulation of USP3 markedly elevated the expression of ACSL4 and promoted ferroptosis in NSCLC cells [71]