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Frontiers in Pharmacology , 15

1B), the protein could not be unfolded within the measurable temperature range indicating that sensitivity of the protein against the two modes of denaturants is different

Interestingly, in vivo studies have shown that serum alkaline phosphatase levels are higher in young children (29 days to 1 year, 50 th percentile: males = 218.19, females = 210.62 U/L) compared to older children (17 to 18 years, 50 th percentile: males = 104.74, females = 75.50 U/L) (25), further supporting the enzyme's relevance during early life when the gut barrier is still developing