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Many of these trials do not adhere to the standards required for high-quality clinical research, such as adequate blinding and randomization, further diminishing their credibility

The side effect profiles of cagrilintide and retatrutide are broadly consistent with other incretin-based therapies, reflecting their shared mechanisms of action

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Generally, the induction of the type I IFN response targets different immune cells from antigen-presenting dendritic cells, T cells to natural killer (NK) cells (200)