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These metabolites exhibit sedative, hypnotic, antidepressant, anxiolytic, and anticonvulsant effects, demonstrating significant potential for application in food, healthcare, and clinical medicine (Wang et al., 2022

In mice, -Klotho is primarily expressed across metabolic tissues including liver, pancreas, and adipose tissue (96, 97)

Thus, a high intake of starch (e.g., 40% on a DM basis) can result in metabolic disorders in cats but not in dogs, whereas dietary fiber is beneficial for the intestinal health of both cats and dogs