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203 "To qualify for certification under Rule 23(b)(3), a proposed class must meet two prerequisites beyond the Rule 23(a) prerequisites." 204 The plaintiff must demonstrate that: These prerequisites are known as "predominance" and "superiority," respectively

In summary, smoke treatments stimulate human macrophages to release IL-8, facilitating inflammation rather than directly enhancing their function while cigarette smoking suppresses the phagocytosis of murine macrophages