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It is also unlikely that the Fe-porphyrin-mediated scavenging role of H 2 would account for all effects seen when, for example, the localization of the production of OH and the diffusion of H 2 from outside the cells - as it is often applied exogenously - are considered

But there is still little clinical research in dogs, and the use in a veterinary practice is still regarded as an investigational/off-label use

This symptom complex typically occurs in asthmatic patients who experience rhinitis with or without nasal polyps, or who exhibit severe, potentially fatal bronchospasm after taking aspirin or other NSAIDs