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Recent studies have found that SLC7A11 expression inhibits M1 polarization in microglia while promoting M2 polarization in OGD models (Zhao et al., 2024)

In addition, DNA methylation influences the expression of T cell cytokines interleukin (IL)-2, IFN-gamma, IL-4 and IL-13,35 36 and the Treg-canonical transcription factor, FOXP3.37 X chromosome inactivation X chromosome inactivation (XCI) in female embryos, which occurs early in zygote development, is also mediated by DNA methylation