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doi: 10.1124/pr.107.07108 243 RivierCRivierJValeW

Sci Signal 3(ra87):87

It is believed that they place a cationic residue near the key cysteine to ensure it is deprotonated, provide a cavity that orients H 2 O 2 for nucleophilic attack, polarize the oxygenoxygen bond that must be split, and provide a proton donor to stabilize the hydroxide product

Biomarkers 14(7):486492 Li X, Mortensen B, Rushfeldt C, Huseby NE (1998) Serum gamma-glutamyltransferase and alkaline phosphatase during experimental liver metastases