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In addition, both HepG2 and HepG2 ATP7B-KO cells showed increased oxidative stress and H 2 O 2 levels after copper treatment, indicating that reactive oxygen species could play a role in WD

Experts recommend the use of bacteriostatic water for this purpose

Utilizing characteristics of the tumor microenvironment, such as acidic environments or excess glutathione, can significantly enhance drug accumulation in tumor cells while reducing toxicity to normal cells (153)