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Glutathione Glutathione (GSH) is a thiol tripeptide found at high concentrations in most cells and is the primary non-enzymatic antioxidant found in ASL [38]

GALC dysfunction results in elevated levels of cytotoxic D -galactosylsphingosine in neural tissues, which leads to extensive degeneration of oligodendrocytes and Schwann cells, followed by destructive demyelination