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In a recent study, Mei Tingfang et al

When we think about aging, we often focus on the cheeks, under eyes, and jowls, but one of the most overlooked areas is the temples

[PMC free article] [PubMed] [Google Scholar] 75.Khayyat A, Tobwala S, Hart M, Ercal N

For example, perturbations of regulatory pathways upstream of lipin-1, including those involving SIRT1 and AMPK (162, 163), can enhance inflammatory signaling in macrophages, indicating that lipin-1-dependent effects on inflammation are highly context-dependent and integrated with other signaling modules