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Anticonvulsant hypersensitivity syndrome, in vitro assessment of risk

Biosci Biotechnol Biochem 61:19771980

We hypothesized that binding of the Src SH3 domain to the central crest region of -arrestin1 (arr1-CC), along with the resulting conformational changes in arr1, could impair its engagement with the transmembrane core of GPCRs (Fig

The basic metabolic process of copper relies on three key copper transporters: SLC31A1 is responsible for copper uptake, while ATP7A and ATP7B are responsible for copper efflux