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Anaesthesist 45(4):343350 Spies CD, Reinhart K, Witt I, Meier-Hellmann A, Hannemann L, Bredle DL, Schaffartzik W (1994) Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study

Rosmarinic acid suppressed cisplatin-induced apoptosis by repressing ROS generation, cytochrome C release, caspase activation, AIF translocation, NF-B activation, IL-1 production, Bax upregulation, and Bcl-2 down-regulation, (Jeong et al

Thus, while identifying ferroptosis as an aspect of the macrophage in CD, much remains to be done to understand the physiological and pathophysiological implications of death pathways in myeloid cells

There is extensive crosstalk between these cell death mechanisms, mainly through processes involving mitochondria, glutathione and the cystine transporter SLC7A11