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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Bradshaw AD, Sage EH

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The ranges below are extrapolated from rodent studies scaled to human bodyweight using allometric conversion, and reflect the most commonly cited research-protocol doses in the practitioner literature

The dermis was then carefully separated from the full-thickness skin specimens and soaked in collagenase solution (collagenase C7657 Sigma, 2 mgmL 1 ) at 37 C for 1 h with gentle agitation