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Collectively, the roadmap toward clinical translation should include systematic human safety and pharmacokinetic studies, biomarker-driven and phenotype-stratified randomized controlled trials, rigorous exploration of combination regimens, and incorporation of patient-centered outcomes

Dihexa is a synthetic peptide originally developed by researchers at Washington State University as part of a program to create therapies for Alzheimers disease and cognitive decline

Patients have to experience a minimum of 15 headaches or more lasting four hours a day or longer per month, according to the FDA

Straus DS, Takemoto CD