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The small form occurs in 1 per 100 live births, the medium form in 6 per 1000 live births, and the incidence of the giant form is globally estimated at 1 in 20,000 to 500,000 live births [4, 9]

If morphology and immunohistochemistry are not contributory in assigning the melanocytic tumor to a given lineage, molecular analysis guided by morphology may be implemented as follows: - Identification of hotspot mutations of BRAF (codon 600) and NRAS [exon 2 (odons 12, 13), exon 3 (codons 59, 61), and of exon 4 (codons 117, 146)]

Mcula melantica (correcta): La mcula melantica (MM) es la lesin de origen melanoctico ms comn de la mucosa oral (3% de la poblacin general)