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If confirmed, that would represent a fundamental shift in how society understands addiction and how doctors treat it

Limitations include the application of ever use in operationalizing the e-cigarette exposure, precluding investigation of doseresponse associations between level of e-cigarette use and odds of becoming an ever smoker, and the omissions of some covariates that may provide a more comprehensive adjustment for endogenous liability to smoking (e.g., sensation seeking, depression)

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Health Canada report calls for big tax hike on cigarettes Health groups want Alberta to raise tobacco tax, bolster anti-smoking programs The increases are gradual, Collishaw said, and are spread between a tobacco company's high- and low-end brands to make them less noticeable to consumers