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Were back to square one, dependent on external systems while local capacity remains weak

Not a traditional cigarette, not an e-cig Instead of generating smoke, the Iqos device produces a vapour that delivers the nicotine from specially-designed "tobacco sticks." This is similar to the way many e-cigarettes currently on the market work, aside from one huge thing: Unlike most e-cigs, the Iqos still contains tobacco

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Functional assays with BEAS-2B cells supported and extended the proteomics findings, demonstrating that mitochondria and the cytoskeleton are primary targets of both aldehydes, accompanied by increased reactive oxygen species (ROS) generation