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Its downregulation has been shown to suppress the degradation of unsaturated fatty acids through multiple mechanisms, including inhibiting the activity of key enzymes involved in fatty acid catabolism (e.g., acetyl-CoA dehydrogenase, lipoxygenase, and fatty acid dioxygenase) and activating the PPAR signaling pathway and its downstream target genes [71]

Some animal research suggests it has potent antiepileptic and neuroprotective effects and, when used correctly, should be safe for healthy adults.25 However, because supplements including nootropic ones arent regulated by the FDA, theres a possibility that supplements containing Huperzia serrata can be dangerous