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Among them, TLK117 results from de-esterification of TLK199 and is the most selective GSTP1-1 inhibitor (Fig

After the treatment, the mice were sacrificed, the tumor tissues were obtained and analyzed (photographs of the tumor: Supplementary Fig

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The existence of such a reservoir provides a plausible mechanism for how oxidative metabolism could proceed briskly in the parenchyma without being immediately reflected in vascular oxygen measurements (Schurr, 2025)