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It was in 1686 that John Clayton, minister at Jamestown, offered proposals for draining the marshes nearby to improve the healthfulness of the spot, a project that never materialized

Selected Drugs or Substances Suspected or Proven to Be Human Teratogens CRITERIA FOR TERATOGENICITY In order to establish a cause-and-effect relationship between a birth defect and prenatal exposure to a certain drug, chemical, or environmental agent, specific criteria are required ( Table 8-2 )

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