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10.3390/nu8080477

[114] [115] Generally speaking, mild cases can cause few symptoms and either need no treatment or can be managed by means of avoiding circumstances which might trigger a crisis, monitoring and occasional treatment

retrospective, real-world analysis of 3965 LT4-treated patients in Italy found that LT4 dose increases before and after a drug-drug indication (mainly due to proton pomp inhibitors and calcium or iron salts) were less likely in individuals taking a liquid LT4 formulation [45]

THC undergoes biotransformation primarily through CYP2C9 and CYP3A4 enzymes , converting to the more potent 11-hydroxy-THC metabolite