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GPX4 prevents ferroptosis by reducing phospholipid peroxidation (Xie et al., 2023)

A compound that keeps cells alive but stops them from replicating looks like a pass in a viability screen, but thats a missed signal you need to catch

Multiple rounds are necessary for some patients (mainly women), and almost all patients experience side effects in high doses as well as a purging period that can last for months

The examination of prior studies resulted in different findings for the same treatment received due to potential confounding variables or biases not considered or not statistically controlled for, as well as considerations of statistical power and analysis, in conjunction with missing data that can affect the outcomes of clinical trials [116] (Fig